Letrozole 28 x 2.5mg UK Pharma can be used in patients working on getting pregnant with PCOS (Polycystic Ovary Syndrome) who have irregular or absent period.

Since, Letrozole blocks aromatase activity, there is a drop in E2 levels and release of the pituitary (hypothalamic) axis from estrogenic negative feedback. The resultant increase in FSH secretion stimulates growth of ovarian follicles.

With aromatase inhibition (AI), there is a temporary increase in androgen levels in the ovary. Androgens are known to increase the sensitivity of the follicles to FSH.

Letrozole (letrozole systemic) is used to treat certain types of breast cancer in women after menopause. It is also used to help prevent the cancer from returning. Since, breast cancers are made to grow faster by a natural hormone called estrogen.

Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of breast cancers.